Pectate disaccharide-lyase

pectate disaccharide-lyase

Identifiers

EC number
4.2.2.9

CAS number
37290-87-2

Databases

IntEnz
IntEnz view

BRENDA
BRENDA entry

ExPASy
NiceZyme view

KEGG
KEGG entry

MetaCyc
metabolic pathway

PRIAM
profile

PDB structures
RCSB PDB PDBe PDBsum

Gene Ontology
AmiGO / EGO

Search

PMC
articles

PubMed
articles

NCBI
proteins

In enzymology, a pectate disaccharide-lyase (EC 4.2.2.9) is an enzyme that catalyzes the chemical reaction

Eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is (1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase. Other names in common use include pectate exo-lyase, exopectic acid transeliminase, exopectate lyase, exopolygalacturonic acid-trans-eliminase, PATE, exo-PATE, and exo-PGL.
References[edit]

Macmillan JD; Vaughn RH (1964). “Purification and properties of a polygalacturonic acid-trans-eliminase produced by Clostridium multifermentans”. Biochemistry. 3 (4): 564–572. doi:10.1021/bi00892a016. PMID 14188174. 

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Carbon-oxygen lyases (EC 4.2) (primarily dehydratases)

4.2.1: Hydro-Lyases

Carbonic anhydrase
Fumarase
Aconitase
Enolase

Alpha
Enolase 2

Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase
Methylglutaconyl-CoA hydratase
Tryptophan synthase
Cystathionine beta synthase
Porphobilinogen synthase
3-Isopropylmalate dehydratase
Urocanase
Uroporphyrinogen III synthase
Nitrile hydratase

4.2.2: Acting on polysaccharides

Hyaluronate lyase

4.2.3: Acting on phosphates

Threonine synthase

4.2.99: Other

Carboxymethyloxysuccinate lyase

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Enzymes

Activity

Active site
Binding site
Catalytic triad
Oxyanion hole
Enzyme promiscuity
Catalytically perfect enzyme
Coenzyme
Cofactor
Enzyme catalysis

Regulation

Allosteric regulation
Cooperativity
Enzyme inhibitor

Classification

EC number
Enzyme superfamily
Enzyme family
List of enzymes

Kinetics

Enzyme kinetics
Eadie–Hofstee diagram
Hanes–Woolf plot
Lineweaver–Burk plot
Michaelis–Menten kinetics

Types

EC1 Oxidoreductases (list)
EC2 Transferases (list)
EC3 Hydrolases (list)
EC4 Lyases (list)
EC5 Isomerases (list)
EC6 Ligases (list)

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